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(2023) investigated the effect of borneol-baicalin liposomes on enhancing brain targeting

In the largest and longest follow-up study to date (up to 12 months), patients with mild AD underwent FUS targeting the hippocampus, frontal, and parietal lobes, with no serious adverse events, full BBB closure within 48 h, and cognitive outcomes comparable to those seen with natural disease progression (Rezai et al., 2022)